Associations between Body Mass Index Trajectories in the first two years of life and Allergic Rhinitis, Eczema and Food Allergy outcomes up to early adulthood

CL Chang; GB Ali; CJ Lodge; MJ Abramson; B Erbas; MLK Tang; C Svanes; DS Bui; SC Dharmage; AJ Lowe

Journal article

Associations between Body Mass Index Trajectories in the first two years of life and Allergic Rhinitis, Eczema and Food Allergy outcomes up to early adulthood

CL Chang, GB Ali, CJ Lodge, MJ Abramson, B Erbas, MLK Tang, C Svanes, DS Bui, SC Dharmage, AJ Lowe

Pediatric Allergy and Immunology | WILEY | Published : 2022

DOI: 10.1111/pai.13765

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Abstract

Background: Early life body mass index (BMI) trajectories influence the risk of asthma at 18 years of age. However, it is unclear if these are also associated with other allergic diseases. Objectives: We investigated the associations between BMI trajectories and subsequent allergic rhinitis, eczema and food sensitisation/allergies. Methods: Parent-reported anthropometric data were collected 18 times in the first two years of life from a cohort of 620 participants in a high-risk cohort. Group-based trajectory modelling was applied to develop BMI trajectories. Associations between trajectories and allergic rhinitis, eczema and food sensitisation at 6, 12 and 18 years of age were assessed using..

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University of Melbourne Researchers

Caroline Lodge Author

Michael Abramson Author

Bircan Erbas Author

Mimi Tang Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The first six years of funding for the MACS was funded by Nestec; a branch of Nestle Australia. For 12-year follow-up, the project was funded by the Asthma Foundation of Victoria. For 18-year follow-up, the study was funded by The National Health and Medical Research Council of Australia [APP454856]. AJL and SCD were supported by National Health and Medical Research Council of Australia Fellowships during the conduct of this research